Merpen 500mg Injection

Merpen 500mg Injection is an ultra-broad-spectrum, sterile intravenous carbapenem antibiotic containing meropenem (as trihydrate). It operates by penetrating bacterial cell walls and binding irreversibly to penicillin-binding proteins (PBPs), disrupting peptidoglycan synthesis and causing rapid bacterial cell lysis. Its molecular structure resists degradation by human renal dehydropeptidase-I, removing any clinical requirement for a protective enzyme inhibitor. This lower-strength configuration is indicated for severe or complicated infections in pediatric patients, adult maintenance dosing, or patients with moderate renal impairment. Primary indications include hospital-acquired pneumonia, complicated intra-abdominal sepsis, severe gynecological infections, complicated urinary tract infections, and skin structure infections. Administration is strictly restricted to intravenous (IV) bolus injection over 3 to 5 minutes or via IV infusion over 15 to 30 minutes, typically scheduled every 8 hours. Merpen 500mg is strictly contraindicated in patients with established hypersensitivity to meropenem or other carbapenems. Dosage modifications are mandatory when creatinine clearance drops below 50ml/min. Common adverse effects include injection site phlebitis, diarrhea, nausea, vomiting, headache, and a potential risk of central nervous system toxicity or seizures.

Price: Rs. 1573.00

• Manufacturer
  Lci Limited
• Generic name
  Meropenem
• Pack size
  1 Vial injection
• Availability
  In stock
• Prescription required
  Yes